Streptozotocin | Streptozocin | Streptozocin | NSC-85998 | U 9889 | CAS: 18883-66-4

规格	库存	目录价	会员专享价	数量
50 mg	In-stock	￥316.00	登录后可见	- +
100 mg	In-stock	￥466.00	登录后可见	- +
200 mg	In-stock	￥788.00	登录后可见	- +

规格

库存

目录价

会员专享价

数量

50 mg

In-stock

￥316.00

登录后可见

- +

100 mg

In-stock

￥466.00

登录后可见

- +

200 mg

In-stock

￥788.00

登录后可见

- +

基本信息

英文名称	Streptozotocin (Synonyms: Streptozocin; Streptozocin; NSC-85998; U 9889)
中文名称	1-甲基-1-亚硝基-3-((2S,3R,4R,5S,6R)-2,4,5-三羟基-6-(羟甲基)四氢-2H-吡喃-3-基)脲; 链脲菌素; 链脲佐菌素
CAS号	18883-66-4
分子式	C8H15N3O7
分子量	265.22
MDL	MFCD00006607
外观	Light yellow powder
储存条件	-20°C, sealed storage, away from moisture and light

产品详情

Streptozotocin (STZ) is a glucosamine-nitrosourea which is commonly used to induce experimental diabetes in animals. It specifically targets beta cells, entering via the glucose transporter GLUT2 and causing alkylation of DNA. DNA damage induces activation of poly ADP-ribosylation, depletion of cellular NAD+ and ATP, and formation of superoxide radicals, leading to the destruction of beta cells.The effectiveness of STZ depends on the level of GLUT2 expression, which in turn may be influenced by age, sex, strain, or species.

1-甲基-1-亚硝基-3-((2S,3R,4R,5S,6R)-2,4,5-三羟基-6-(羟甲基)四氢-2H-吡喃-3-基)脲; 链脲菌素; 链脲佐菌素

Streptozotocin (Synonyms: Streptozocin; Streptozocin; NSC-85998; U 9889)

化学品安全说明书(MSDS)

质检证书(COA)