Tofacitinib Citrate | Tasocitinib Citrate | CP-690550 Citrate | CAS 540737-29-9 |JAK

规格	库存	目录价	会员专享价	数量
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规格

库存

目录价

会员专享价

数量

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基本信息

英文名称	Tofacitinib Citrate \| Tasocitinib Citrate \| CP-690550 Citrate
中文名称	枸橼酸托法替尼丨枸橼酸托法替布
CAS号	540737-29-9
分子式	C16H20N6O.C6H8O7
分子量	504.49
外观	White to off-white powder
储存条件	4°C, sealed storage, away from moisture and light

产品详情

Tofacitinib, also known as tasocitinib, CP-690550, is a Janus kinase (JAK) inhibitor. Tofacitinib modulates the signaling pathway at the point of JAKs, preventing the phosphorylation and activation of STATs. JAK enzymes transmit cytokine signaling through pairing of JAKs (e.g., JAK1/JAK3, JAK1/JAK2, JAK1/TyK2, JAK2/JAK2). Tofacitinib inhibited the in vitro activities of JAK1/JAK2, JAK1/JAK3, and JAK2/JAK2 combinations with IC50 of 406, 56, and 1377 nM, respectively.

枸橼酸托法替尼丨枸橼酸托法替布

Tofacitinib Citrate | Tasocitinib Citrate | CP-690550 Citrate

化学品安全说明书(MSDS)