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規格	庫存	目錄價	會員專享價	數量
5 mg	3-5days	￥366.00	登錄后可見	- +
10 mg	3-5days	￥636.00	登錄后可見	- +
25 mg	3-5days	￥1066.00	登錄后可見	- +

規格

庫存

目錄價

會員專享價

數量

5 mg

3-5days

￥366.00

登錄后可見

- +

10 mg

3-5days

￥636.00

登錄后可見

- +

25 mg

3-5days

￥1066.00

登錄后可見

- +

基本信息

英文名稱	H-89 Dihydrochloride \| H 89 2HCl
中文名稱	H-89二鹽酸鹽
CAS號	130964-39-5
分子式	C20H20BrN3O2S· 2HCl
分子量	519.28 \| 446.36(free)
外觀	White to light yellow powder
儲存條件	4°C, sealed storage, away from moisture

產品詳情

H-89 dihydrochloride is a potent and selective inhibitor of protein kinase A (PKA) with an IC₅₀ of 48 nM and has weak inhibition on PKG, PKC, Casein Kinase.

相關文獻

Inhibition of forskolin-induced neurite outgrowth and protein phosphorylation by a newly synthesized selective inhibitor of cyclic AMP-dependent protein kinase, N-[2-(p-bromocinnamylamino)ethyl]-5-isoquinolinesulfonamide (H-89), of PC12D pheochromocytoma cells.

PMID: 2156866

Specificity and mechanism of action of some commonly used protein kinase inhibitors.

PMID: 10998351 PMCID: PMC1221339 DOI: 10.1042/0264-6021:3510095

Effects of BL-191 and H-89 on epileptogenic activity of bucladesine in pentylenetetrazol-treated mice.

PMID: 21946102 DOI: 10.1016/j.ejphar.2011.09.026

Effects of the PKA inhibitor H-89 on excitation-contraction coupling in skinned and intact skeletal muscle fibres.

PMID: 11763200 DOI: 10.1023/a:1012289526618