鹽酸多柔比星 | 鹽酸阿霉素

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Doxorubicin(Adriamycin) Hydrochloride | Doxorubicin HCl

產品編號：CL1004 CAS No.：25316-40-9 MDLNo： 分子式：C27H29NO11.HCl 分子量： 579.98

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規格	庫存	目錄價	會員專享價	數量
100 mg	In-stock	￥260.00	登錄后可見	- +
500 mg	In-stock	￥750.00	登錄后可見	- +
1 g	In-stock	￥1260.00	登錄后可見	- +

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基本信息
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基本信息

英文名稱	Doxorubicin(Adriamycin) Hydrochloride \| Doxorubicin HCl
中文名稱	鹽酸多柔比星 \| 鹽酸阿霉素
CAS號	25316-40-9
分子式	C27H29NO11.HCl
分子量	579.98
外觀	Orange red powder
儲存條件	Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years).

產品詳情

Doxorubicin is an anthracycline antibiotic with antineoplastic activity. Doxorubicin, isolated from the bacterium Streptomyces peucetius var. caesius, is the hydroxylated congener of daunorubicin. Doxorubicin intercalates between base pairs in the DNA helix, thereby preventing DNA replication and ultimately inhibiting protein synthesis. Additionally, doxorubicin inhibits topoisomerase II which results in an increased and stabilized cleavable enzyme-DNA linked complex during DNA replication and subsequently prevents the ligation of the nucleotide strand after double-strand breakage. Doxorubicin also forms oxygen free radicals resulting in cytotoxicity secondary to lipid peroxidation of cell membrane lipids; the formation of oxygen free radicals also contributes to the toxicity of the anthracycline antibiotics, namely the cardiac and cutaneous vascular effects.

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CL1004

鹽酸多柔比星 | 鹽酸阿霉素

25316-40-9 98+% In-stock

￥260.00 100 mg