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規(guī)格	庫存	目錄價	會員專享價	數(shù)量
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庫存

目錄價

會員專享價

數(shù)量

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基本信息

英文名稱	NVP-AUY922 \| Luminespib \| AUY922 \| VER-52296
中文名稱	NVP-AUY922 \| Luminespib \| AUY922 \| VER-52296
CAS號	747412-49-3
分子式	C26H31N3O5
分子量	465.54
外觀	Light yellow to gray powder
儲存條件	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

產(chǎn)品詳情

Luminespib (VER-52296) is an HSP90 inhibitor that inhibits HSP90α and HSP90β (IC50=7.8/21 nM). Luminespib has antitumor activity and is used in studies of head and neck tumors, among others.

相關文獻

NVP-AUY922: A Novel Heat Shock Protein 90 Inhibitor Active against Xenograft Tumor Growth, Angiogenesis, and Metastasis.

PMID: 18413753 DOI: 10.1158/0008-5472.CAN-07-5256

Heat shock protein-90 inhibitor, NVP-AUY922, is effective in combination with NSC 118218 against chronic lymphocytic leukemia cells cultured on CD40L-stromal layer and inhibits their activated/proliferative phenotype.

PMID: 22646928 DOI: 10.3109/10428194.2012.698278

Stoeltzing O.Targeting HSP90 by the novel inhibitor NVP-AUY922 reduces growth and angiogenesis of pancreatic cancer.

PMID: 22753713

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