寡霉素 A

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Oligomycin A | MCH 32

產品編號：CL1981 CAS No.：579-13-5 MDLNo： 分子式：C45H72O11 分子量：789.05

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基本信息

英文名稱	Oligomycin A \| MCH 32
中文名稱	寡霉素 A
CAS號	579-13-5
分子式	C45H72O11
分子量	789.05
外觀	White to off-white
儲存條件	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

產品詳情

Oligomycin A, also known as MCH 32, is an inhibitor of ATP synthase. Oligomycin A inhibits ATP synthase by blocking its proton channel (Fo subunit), which is necessary for oxidative phosphorylation of ADP to ATP (energy production). The inhibition of ATP synthesis by oligomycin A will significantly reduce electron flow through the electron transport chain; however, electron flow is not stopped completely due to a process known as proton leak or mitochondrial uncoupling. This process is due to facilitated diffusion of protons into the mitochondrial matrix through an uncoupling protein such as thermogenin, or UCP1.

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