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普伐他汀鈉

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Pravastatin Sodium

產(chǎn)品編號(hào):CL2193 CAS No.:81131-70-6 MDLNo: 分子式:C23H35O7.Na 分子量:446.51
規(guī)格 庫(kù)存 目錄價(jià) 會(huì)員專享價(jià) 數(shù)量
10 mg In-stock ¥170.00 登錄后可見
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25 mg In-stock ¥320.00 登錄后可見
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50 mg In-stock ¥450.00 登錄后可見
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100 mg In-stock ¥750.00 登錄后可見
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基本信息
英文名稱 Pravastatin Sodium
中文名稱普伐他汀鈉
CAS號(hào)81131-70-6
分子式C23H35O7.Na
分子量446.51
外觀Off-white to Pale purple powder
儲(chǔ)存條件 Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
產(chǎn)品詳情

 Pravastatin sodium (CS-514) is an HMG-CoA reductase inhibitor against sterol synthesis with IC50 of 5.6 μM.

 Pravastatin Sodium is an antilipemic fungal metabolite isolated from cultures of Nocardia autotrophica. It acts as a competitive inhibitor of HMG CoA reductase Pravastatin competitively inhibits hepatic hydroxymethyl-glutaryl coenzyme A reductase, the enzyme which catalyzes the conversion of HMG-CoA to mevalonate, a key step in cholesterol synthesis. This agent lowers plasma cholesterol and lipoprotein levels, and modulates immune responses by suppressing MHC II on interferon gamma-stimulated, antigen-presenting cells such as human vascular endothelial cells.

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