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達薩布韋 | 達塞布韋

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Dasabuvir | ABT-333

產(chǎn)品編號:CL2455 CAS No.:1132935-63-7 MDLNo: 分子式:C26H27N3O5S 分子量:493.57
規(guī)格 庫存 目錄價 會員專享價 數(shù)量
10 mg In-stock ¥600.00 登錄后可見
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25 mg In-stock ¥980.00 登錄后可見
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50 mg In-stock ¥1568.00 登錄后可見
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基本信息
英文名稱 Dasabuvir | ABT-333
中文名稱達薩布韋 | 達塞布韋
CAS號1132935-63-7
分子式C26H27N3O5S
分子量493.57
外觀White to yellow powder
儲存條件Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
產(chǎn)品詳情

Dasabuvir (formerly known as ABT-333; ABT333; trade name Exviera, Viekira Pak, Viekira XR) is a nonnucleoside inhibitor of the RNA-dependent RNA polymerase encoded by the hepatitis C virus (HCV) NS5B gene. It inhibited recombinant NS5B polymerases derived from HCV genotype 1a and 1b clinical isolates, with IC50 values between 2.2 and 10.7 nM, and was at least 7,000-fold selective for the inhibition of HCV genotype 1 polymerases over human/mammalian polymerases. Dasabuvir is an FDA approved antiviral medication for the treatment of hepatitis C. It is often used together with the combination medication ombitasvir/paritaprevir/ritonavir specifically for hepatitis C virus (HCV) type 1.

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