奎扎替尼

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Quizartinib (AC220)

產品編號：CL2519 CAS No.：950769-58-1 MDLNo： 分子式：C29H32N6O4S 分子量：560.67

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規格	庫存	目錄價	會員專享價	數量
5 mg	3-5days	￥450.00	登錄后可見	- +
10 mg	3-5days	￥650.00	登錄后可見	- +
25 mg	3-5days	￥950.00	登錄后可見	- +

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基本信息
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基本信息

英文名稱	Quizartinib (AC220)
中文名稱	奎扎替尼
CAS號	950769-58-1
分子式	C29H32N6O4S
分子量	560.67
外觀	White to off-white powder
儲存條件	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

產品詳情

Quizartinib (formerly also know as AC-220; AC-010220, Vanflyta) is a novel, potent, 2nd-generation, and orally bioavailable FLT3 tyrosine kinase inhibitor for Flt3 (ITD/WT) with potential anticancer activity.With IC50s of 1.1 nM and 4.2 nM, respectively, it inhibits FLT3 in MV4-11 and RS4EL11 cells. With respect to KIT, PDGFRα, PDGFRβ, RET, and CSF-1R, it demonstrates a ten-fold greater selectivity. Currently, Daiichi Sankyo is developing quizartinib to treat acute myeloid leukemia. Quizartinib (Vanflyta) was approved in 2023 by FDA for treating AML.

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CL2519

奎扎替尼

950769-58-1 98+% 3-5days

￥450.00 5 mg