Sotuletinib (BLZ945)

ChemLeader 98+%

Sotuletinib (BLZ945)

產品編號：CL2550 CAS No.：953769-46-5 MDLNo： 分子式：C20H22N4O3S 分子量：398.48

加入收藏分享給朋友

規格	庫存	目錄價	會員專享價	數量
5 mg	3-5days	￥600.00	登錄后可見	- +
10 mg	3-5days	￥900.00	登錄后可見	- +
25 mg	3-5days	￥1600.00	登錄后可見	- +

化學品安全說明書(MSDS)

下載MSDS

發送詢價加入購物車

基本信息
相關文檔
產品詳情
相關文獻

基本信息

英文名稱	Sotuletinib (BLZ945)
中文名稱	Sotuletinib (BLZ945)
CAS號	953769-46-5
分子式	C20H22N4O3S
分子量	398.48
外觀	Off-white to light brown powder
儲存條件	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

產品詳情

Sotuletinib (formerly BLZ945; BLZ-945) is a novel, potent, selective, orally bioactive, and brain-penetrant CSF-1R (colony stimulating factor 1 receptor) inhibitor with potential antitumor activity. It exhibits 1000-fold higher selectivity against its closest receptor tyrosine kinase homologs and inhibits CSF-1R with an IC50 of 1 nM. Glioma-bearing mice demonstrate high in vivo antitumor efficaciousness of BLZ945. Sotuletinib was designated as an orphan drug by the US FDA in August 2022 in order to treat patients suffering from Amyotrophic Lateral Sclerosis (ALS), a progressive neurological disorder that affects nerve cells in the brain and spinal cord and results in loss of motor control.

相關文獻

抱歉，暫時沒有相關文獻

相關產品

抱歉，暫時沒有相關產品

瀏覽記錄

CL2550

Sotuletinib (BLZ945)

953769-46-5 98+% 3-5days

￥600.00 5 mg