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規格	庫存	目錄價	會員專享價	數量
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規格

庫存

目錄價

會員專享價

數量

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基本信息

英文名稱	NS-398(Synonyms: N-[2-(Cyclohexyloxy)-4-nitrophenyl]methanesulfonamide )
中文名稱	N-[2-(環己基氧基)-4-硝基苯基]甲烷磺酰胺
CAS號	123653-11-2
分子式	C13H18N2O5S
分子量	314.36
MDL	MFCD00882995
外觀	Light yellow to yellow powder

產品詳情

NS-398 is a non-steroidal anti-inflammatory drug with analgesic properties, which can be used in the study of pain relief. It selectively inhibits the activity of COX-2 with an IC50 value of 3.8 μM and has no effect on the activity of COX-1 at a concentration of 100 μM.

相關文獻

A Research Article Submitted to Journal of Ethnopharmacology Naoxintong restores Ischemia Injury and inhibits Thrombosis via COX2-VEGF/NFκB Signaling[J].

https://doi.org/10.1016/j.jep.2021.113809

All-trans retinoic acid and COX-2 cross-talk to regulate BMP9-induced osteogenic differentiation via Wnt/β-catenin in mesenchymal stem cells[J].

https://doi.org/10.1016/j.biopha.2019.109279

NS-398, a new anti-inflammatory agent, selectively inhibits prostaglandin G/H synthase/cyclooxygenase (COX-2) activity in vitro.

PMID: 8140262 DOI: 10.1016/0090-6980(94)90074-4

NS-398, a novel non-steroidal anti-inflammatory drug with potent analgesic and antipyretic effects, which causes minimal stomach lesions.

Gen Pharmacol. 1993 Jan;24(1):105-10.