英文名稱 | HA14-1 |
---|---|
中文名稱 | rel-(αR,4R)-2-氨基-6-溴-4-(1-氰基-2-乙氧基-2-甲酰)-4H-苯并呋喃-3-羧酸 |
CAS號 | 65673-63-4 |
分子式 | C17H17BrN2O5 |
分子量 | 409.23 |
MDL | MFCD00218213 |
外觀 | White to light yellow powder |
儲存條件 | Store short-term at 0-4°C or long-term at -20°C in a dry, dark place. |
英文名稱 | HA14-1 |
---|---|
中文名稱 | rel-(αR,4R)-2-氨基-6-溴-4-(1-氰基-2-乙氧基-2-甲酰)-4H-苯并呋喃-3-羧酸 |
CAS號 | 65673-63-4 |
分子式 | C17H17BrN2O5 |
分子量 | 409.23 |
MDL | MFCD00218213 |
外觀 | White to light yellow powder |
儲存條件 | Store short-term at 0-4°C or long-term at -20°C in a dry, dark place. |
HA14-1, a Bcl-2/Bcl-XL antagonist, is a non-peptidic ligand of a Bcl-2 surface pocket (IC50: ~9 μM).
Initiation of apoptosis and autophagy by the Bcl-2 antagonist HA14-1.
PMID: 17055152 PMCID: PMC1924967 DOI: 10.1016/j.canlet.2006.09.009
PMID: 16510597 DOI: 10.1158/0008-5472.CAN-05-2097
PMID: 10860979 PMCID: PMC16510 DOI: 10.1073/pnas.97.13.7124