英文名稱 | Exendin-4 (Synonyms: Exenatide) |
---|---|
中文名稱 | 艾塞那肽 |
CAS號 | 141732-76-5 |
分子式 | C181H278N50O58 S |
分子量 | 4,114.51 |
外觀 | White to off-white powder |
儲存條件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
英文名稱 | Exendin-4 (Synonyms: Exenatide) |
---|---|
中文名稱 | 艾塞那肽 |
CAS號 | 141732-76-5 |
分子式 | C181H278N50O58 S |
分子量 | 4,114.51 |
外觀 | White to off-white powder |
儲存條件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Exendin-4, also known as Exenatide, is a 39-amino acid peptide that acts as a potent and long-acting GLP-1 receptor agonist, with an IC50 of 3.22 nM.
PMID: 27072494 DOI: 10.1152/ajpendo.00400.2015
Antidiabetic exendin-4 activates apoptotic pathway and inhibits growth of breast cancer cells.
Tumour Biol. 2016 Feb;37(2):2647-53.
Hepatology. 2006 Jan;43(1):173-81.