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規(guī)格	庫(kù)存	目錄價(jià)	會(huì)員專享價(jià)	數(shù)量
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規(guī)格

庫(kù)存

目錄價(jià)

會(huì)員專享價(jià)

數(shù)量

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基本信息

英文名稱	Sepinol
中文名稱	Sepinol
CAS號(hào)	72061-63-3
分子式	C16H14O7
分子量	318.28
儲(chǔ)存條件	Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃.

產(chǎn)品詳情

Sepinol is a chromene-type natural product that is structurally related to the flavonoid class of plant compounds. This compound has been shown to inhibit LPS-induced macrophage activation and proinflammatory cytokine production in vitro. Sepinol also inhibits the production of reactive oxygen species by macrophages, which is thought to be due to its ability to inhibit NADPH oxidase activity and the expression of HIF-1α, a transcription factor that regulates many genes involved in inflammation. Sepinol also contains a hydroxy group on its chromene ring, which may explain its chromatographic behavior as well as its resistance against oxidative degradation. The conformation of this molecule suggests that it could be substituted at positions 2 or 3 with a hydroxy group.

相關(guān)文獻(xiàn)

Structure-activity relationship of the inhibitory effects of flavonoids on nitric oxide production in RAW264.7 cells.

https://doi.org/10.1016/j.bmc.2016.11.055

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Sepinol

Sepinol

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