英文名稱(chēng) | Y-27632 (free base) |
---|---|
中文名稱(chēng) | Y-27632 |
CAS號(hào) | 146986-50-7 |
分子式 | C14H21N3O |
分子量 | 247.34 |
外觀 | White to off-white powder |
儲(chǔ)存條件 | -20°C, protect from light, stored under nitrogen |
規(guī)格 | 庫(kù)存 | 目錄價(jià) | 會(huì)員專(zhuān)享價(jià) | 數(shù)量 |
---|---|---|---|---|
5 mg | In-stock | ¥556.00 | 登錄后可見(jiàn) | |
10 mg | In-stock | ¥898.00 | 登錄后可見(jiàn) | |
25 mg | In-stock | ¥1436.00 | 登錄后可見(jiàn) |
英文名稱(chēng) | Y-27632 (free base) |
---|---|
中文名稱(chēng) | Y-27632 |
CAS號(hào) | 146986-50-7 |
分子式 | C14H21N3O |
分子量 | 247.34 |
外觀 | White to off-white powder |
儲(chǔ)存條件 | -20°C, protect from light, stored under nitrogen |
Y-27632 is a potent and selective inhibitor of ROCK1 (p160ROCK) with IC50 of 140 nM in a cell-free assay, it exhibits >200-fold selectivity over other kinases, including PKC, cAMP-dependent protein kinase, MLCK and PAK.
PMID: 27591478 DOI: 10.1016/j.scr.2016.07.009