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規格	庫存	目錄價	會員專享價	數量
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規格

庫存

目錄價

會員專享價

數量

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基本信息

英文名稱	LY294002 hydrochloride
中文名稱	LY294002 HCl
CAS號	934389-88-5
分子式	C19H17NO3·HCl
分子量	343.80 \| 307.35
儲存條件	Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃.

產品詳情

LY-294002 hydrochloride (NSC 697286) is a synthetic molecule inhibitor of PI3Kα/δ/β (IC50: 0.5/0.57/0.97 μM, in cell-free assays); more stable than Wortmannin in solution, and also is a blocker of autophagosome formation.

相關文獻

Exploring the specificity of the PI3K family inhibitor LY2942002.

PMID: 17302559 PMCID: PMC1868829 DOI: 10.1042/BJ20061489

In vivo and in vitro ovarian carcinoma growth inhibition by a phosphatidylinositol 3-kinase inhibitor (LY2942002).

PMID: 10741711

The in vitro and in vivo effects of 2-(4-morpholinyl)-8-phenyl-chromone (LY2942002), a specific inhibitor of phosphatidylinositol 3'-kinase, in human colon cancer cells.

PMID: 12060641

Evidence for functional redundancy of class IA PI3K isoforms in insulin signalling.

PMID: 17362206 PMCID: PMC1896275 DOI: 10.1042/BJ20070003